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Home > Nucleosome Maps of the Saccharomyces Genome

chromatinKnowledge of where all the functional elements are located in a eukaryotic genome cannot by itself unleash an understanding of gene regulation as these elements operate in the context of chromatin, where DNA is wrapped around a core of eight histone proteins and packaged into higher order structures.

Functional elements might interchange between these chromatin contexts depending upon the temporal, spatial, and environmental state of the cell. Our research aims to provide a better understanding of where the functional elements reside in relation to nucleosomes.


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Updated on October 8, 2009