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psumark The  Penn State Genome Cartography Project is a collaboration between Penn State's Center for Eukaryotic Gene Regulation and Center for Comparative Genomics and Bioinformatics to map DNA sequence features, protein-nucleic acid interactions, and other information to the genomes of model organisms, and present that information in a visually cognitive way that provides a discovery pathway for biological knowledge.

Current Projects

Knowledge of where all the functional elements are located in a eukaryotic genome cannot by itself unleash an understanding of gene regulation as these elements operate in the context of chromatin, where DNA is wrapped around a core of eight histone proteins and packaged into higher order structures. Our research aims to provide a better understanding of where the functional elements reside in relation to nucleosomes.

People

We seek to foster collaborative, interdisciplinary research into fundamental gene regulation processes and their impact on cellular and developmental biology.